Mouse Gfra4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Gfra4
Locus ID	14588
Kit Components	GA201598G1, Gfra4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201598G2, Gfra4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201598G3, Gfra4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001136063, NM_001271001, NM_001271002, NM_020014
Synonyms	AW060733; G630015H18Rik
Summary	This gene encodes a transmembrane protein that functions as the receptor for persephin, a member of the glial cell line derived neurotrophic factors. The encoded protein undergoes proteolytic processing to generate a glycosylphosphatidylinositol-anchored cell surface coreceptor that forms a complex with the receptor tyrosine kinase Ret. A complete lack of the encoded protein impairs production of thyroid calcitonin and increases the rate of bone formation in young mice. [provided by RefSeq, Jul 2016]

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