Mouse Glp1r activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Glp1r
Locus ID	14652
Kit Components	GA201634G1, Glp1r gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201634G2, Glp1r gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201634G3, Glp1r gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_021332
Synonyms	GLP-1R; GLP1Rc
Summary	G-protein coupled receptor for glucagon-like peptide 1 (GLP-1) (PubMed:9568699). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels (By similarity). Plays a role in regulating insulin secretion in response to GLP-1 (PubMed:9568699).[UniProtKB/Swiss-Prot Function]

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