Mouse Gnrh1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Gnrh1
Locus ID	14714
Kit Components	GA201677G1, Gnrh1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201677G2, Gnrh1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201677G3, Gnrh1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_008145, NR_133010
Synonyms	Gnrh; Gnrh2; hpg; LHRH; Lhrh1; Lnrh
Summary	This gene encodes hypophysiotropic peptides belonging to the family of gonadotropin-releasing hormones that stimulate the release of gonadotropins and suppress secretion of prolactin from the pituitary gland. The encoded protein is proteolytically processed to generate two biologically active mature peptides. A deletional mutation encompassing the distal half of this gene in mice resulting in the loss of the encoded protein leads to hypogonadism and infertility. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]

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