Mouse Cxcl1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cxcl1
Locus ID	14825
Kit Components	GA201749G1, Cxcl1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201749G2, Cxcl1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201749G3, Cxcl1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_008176
Synonyms	Fsp; gro; Gro1; KC; Mgsa; N51; Scyb1
Summary	This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This secretory protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils. In mouse, deficiency of this gene is associated with colitis and with defects in immune cell recruitment to the lung. [provided by RefSeq, Apr 2013]

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