Mouse Hells activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Hells
Locus ID	15201
Kit Components	GA201872G1, Hells gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201872G2, Hells gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201872G3, Hells gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_008234
Synonyms	AI323785; E130115I21Rik; LSH; Lysh; PASG; YFK8
Summary	Plays an essential role in normal development and survival. Involved in regulation of the expansion or survival of lymphoid cells. Required for de novo or maintenance DNA methylation. May control silencing of the imprinted CDKN1C gene through DNA methylation. May play a role in formation and organization of heterochromatin, implying a functional role in the regulation of transcription and mitosis.[UniProtKB/Swiss-Prot Function]

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