Mouse Foxd3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Foxd3
Locus ID	15221
Kit Components	GA201886G1, Foxd3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201886G2, Foxd3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201886G3, Foxd3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_010425
Synonyms	CWH3; Genesis; Hfh2
Summary	Binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT-3' and acts as a transcriptional repressor. Also acts as a transcriptional activator. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis.[UniProtKB/Swiss-Prot Function]

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