Mouse Hmox2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Hmox2
Locus ID	15369
Kit Components	GA201927G1, Hmox2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201927G2, Hmox2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201927G3, Hmox2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001136066, NM_010443, NM_001357050
Synonyms	HO-2; HO2
Summary	Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme oxygenase 2 could be implicated in the production of carbon monoxide in brain where it could act as a neurotransmitter.[UniProtKB/Swiss-Prot Function]

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