Mouse Icam2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Icam2
Locus ID	15896
Kit Components	GA202048G1, Icam2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202048G2, Icam2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202048G3, Icam2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_010494
Synonyms	CD102; Icam-2; Ly-60
Summary	ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.[UniProtKB/Swiss-Prot Function]

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