Mouse Ihh activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ihh
Locus ID	16147
Kit Components	GA202108G1, Ihh gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202108G2, Ihh gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202108G3, Ihh gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001313683, NM_010544
Synonyms	HHG-2
Summary	Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones. Induces the expression of parathyroid hormone-related protein (PTHRP).[UniProtKB/Swiss-Prot Function]

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