Mouse Cd74 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cd74
Locus ID	16149
Kit Components	GA202109G1, Cd74 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202109G2, Cd74 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202109G3, Cd74 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001042605, NM_010545
Synonyms	CLIP; DHLAG; HLADG; Ia-GAMMA; Ii
Summary	Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. Enhance also the stimulation of T-cell responses through interaction with CD44.[UniProtKB/Swiss-Prot Function]

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