Mouse Il11ra1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Il11ra1
Locus ID	16157
Kit Components	GA202116G1, Il11ra1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202116G2, Il11ra1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202116G3, Il11ra1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001163401, NM_001172054, NM_010549
Synonyms	AI314697; GP130; Il-11ra; Il11ra; Il11ra2; NR1
Summary	Receptor for interleukin-11. The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells. Essential for the normal development of craniofacial bones and teeth.[UniProtKB/Swiss-Prot Function]

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