Mouse Il6ra activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Il6ra
Locus ID	16194
Kit Components	GA202150G1, Il6ra gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202150G2, Il6ra gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202150G3, Il6ra gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001310676, NM_010559
Synonyms	CD126; IL-6R; IL-6R-alpha; IL-6RA; Il6r
Summary	Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis.[UniProtKB/Swiss-Prot Function]

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