Mouse Irs1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Irs1
Locus ID	16367
Kit Components	GA202184G1, Irs1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202184G2, Irs1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202184G3, Irs1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_010570
Synonyms	G972R; IRS-1
Summary	May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similarity).[UniProtKB/Swiss-Prot Function]

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