Mouse Itgb7 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Itgb7
Locus ID	16421
Kit Components	GA202210G1, Itgb7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202210G2, Itgb7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202210G3, Itgb7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_013566
Synonyms	Ly69
Summary	Integrin alpha-4/beta-7 (Peyer patches-specific homing receptor LPAM-1) is involved in adhesive interactions of leukocytes. It is a receptor for fibronectin and recognizes one or more domains within the alternatively spliced CS-1 region of fibronectin. Integrin alpha-4/beta-7 is also a receptor for MADCAM1 and VCAM1. It recognizes the sequence L-D-T in MADCAM1. Integrin alpha-E/beta-7 is a receptor for E-cadherin.[UniProtKB/Swiss-Prot Function]

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