Mouse Kcnq2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Kcnq2
Locus ID	16536
Kit Components	GA202285G1, Kcnq2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202285G2, Kcnq2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202285G3, Kcnq2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001003824, NM_001003825, NM_001006668, NM_001006669, NM_001006674, NM_001006675, NM_001006676, NM_001006677, NM_001006678, NM_001006679, NM_001006680, NM_001302888, NM_010611
Synonyms	HNSPC; KQT2; Nmf134
Summary	Associates with KCNQ3 to form a potassium channel with essentially identical properties to the channel underlying the native M-current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons as well as the responsiveness to synaptic inputs. Therefore, it is important in the regulation of neuronal excitability.[UniProtKB/Swiss-Prot Function]

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