Mouse Kl activation kit by CRISPRa

CAT#: GA202322

Kl CRISPRa kit - CRISPR gene activation of mouse klotho



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CNY 12255.00


货期*
4周

规格
    • 1 kit

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Kl Antibody - N-terminal region
    • 50 ug

CNY 4628.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol Kl
Locus ID 16591
Kit Components

GA202322G1, Kl gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA202322G2, Kl gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA202322G3, Kl gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Reference Data
RefSeq NM_013823
Synonyms alpha-kl
Summary May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 241 and 874, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D. Essential factor for the specific interaction between FGF23 and FGFR1.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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