Mouse Kl activation kit by CRISPRa
CAT#: GA202322
Kl CRISPRa kit - CRISPR gene activation of mouse klotho
CNY 12255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Kl |
Locus ID | 16591 |
Kit Components | GA202322G1, Kl gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202322G2, Kl gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202322G3, Kl gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Reference Data | |
RefSeq | NM_013823 |
Synonyms | alpha-kl |
Summary | May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 241 and 874, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D. Essential factor for the specific interaction between FGF23 and FGFR1.[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN508816 | Kl - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8680.00 |