Mouse Ldlr activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ldlr
Locus ID	16835
Kit Components	GA202435G1, Ldlr gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202435G2, Ldlr gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202435G3, Ldlr gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001252658, NM_001252659, NM_010700
Synonyms	Hlb301
Summary	Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits.[UniProtKB/Swiss-Prot Function]

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