Mouse Cnmd activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cnmd
Locus ID	16840
Kit Components	GA202436G1, Cnmd gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202436G2, Cnmd gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202436G3, Cnmd gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001310655, NM_010701
Synonyms	Bricd3; ChM-I; Chmd; Lect1
Summary	Bifunctional growth regulator that stimulates the growth of cultured chondrocytes in the presence of basic fibroblast growth factor (FGF) but inhibits the growth of cultured vascular endothelial cells. May contribute to the rapid growth of cartilage and vascular invasion prior to the replacement of cartilage by bone during endochondral bone development (By similarity). Inhibits in vitro tube formation and mobilization of endothelial cells (By similarity). Plays a role as antiangiogenic factor in cardiac valves to suppress neovascularization.[UniProtKB/Swiss-Prot Function]

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