Mouse Lhx3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Lhx3
Locus ID	16871
Kit Components	GA202452G1, Lhx3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202452G2, Lhx3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202452G3, Lhx3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001039653, NM_010711
Synonyms	Lim3; mLim-3; mLIM3; P-LIM
Summary	Required for the establishment of the specialized cells of the pituitary gland and the nervous system (By similarity). Involved in the development of interneurons and motor neurons in cooperation with LDB1 and ISL1. Acts as a transcriptional activator. Binds to and activates the promoter of the alpha-glycoprotein gene, and synergistically enhances transcription from the prolactin promoter in cooperation with Pou1f1/Pit-1.[UniProtKB/Swiss-Prot Function]

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