Mouse Lrrfip1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Lrrfip1
Locus ID	16978
Kit Components	GA202496G1, Lrrfip1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202496G2, Lrrfip1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202496G3, Lrrfip1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001111311, NM_001111312, NM_001310732, NM_008515
Synonyms	AU024550; Fliiap1
Summary	Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA (By similarity). Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding (By similarity).[UniProtKB/Swiss-Prot Function]

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