Mouse Il1rl1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Il1rl1
Locus ID	17082
Kit Components	GA202524G1, Il1rl1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202524G2, Il1rl1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202524G3, Il1rl1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001025602, NM_001294171, NM_010743
Synonyms	DER4; Fit-1; Ly84; St2; St2-rs1; ST2L; T1; T1/ST2
Summary	Receptor for interleukin-33 (IL-33); signaling requires association of the coreceptor IL1RAP (PubMed:18450470, PubMed:17675517). Its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8 (By similarity). Possibly involved in helper T-cell function.[UniProtKB/Swiss-Prot Function]

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