Mouse Mfge8 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Mfge8
Locus ID	17304
Kit Components	GA202648G1, Mfge8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202648G2, Mfge8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202648G3, Mfge8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001045489, NM_008594
Synonyms	AA408458; AI325141; lactadherin; MFG-E8; Mfgm; MP47; P47; SED1
Summary	Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction (By similarity). Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization.[UniProtKB/Swiss-Prot Function]

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