Mouse Map6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Map6
Locus ID	17760
Kit Components	GA202741G1, Map6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202741G2, Map6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202741G3, Map6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001043355, NM_001048167, NM_010837
Synonyms	2810411E12Rik; Map-6; Mtap6; STOP
Summary	Involved in microtubule stabilization in many cell types, including neuronal cells (PubMed:9600916). Specifically has microtubule cold stabilizing activity (PubMed:9600916). Involved in dendrite morphogenesis and maintenance by regulating lysosomal trafficking via its interaction with TMEM106B (By similarity). Regulates KIF5A-mediated axonal cargo transport (By similarity). Regulates axonal growth during neuron polarization (PubMed:28521134).[UniProtKB/Swiss-Prot Function]

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