Mouse Myh9 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Myh9
Locus ID	17886
Kit Components	GA202792G1, Myh9 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202792G2, Myh9 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202792G3, Myh9 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_022410, NM_181327
Synonyms	Fltn; Myhn-1; Myhn1; NMHCIIA; NMMHC-A; NMMHC-IIA; TU72.6
Summary	During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts formation (in the margins but not the central part of spreading cells), and lamellipodial retraction; this function is mechanically antagonized by MYH10 (By similarity). Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping.[UniProtKB/Swiss-Prot Function]

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