Mouse Nek1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Nek1
Locus ID	18004
Kit Components	GA202859G1, Nek1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202859G2, Nek1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202859G3, Nek1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001293637, NM_001293638, NM_001293639, NM_175089
Synonyms	D8Ertd790e; kat
Summary	Phosphorylates serines and threonines, but also appears to possess tyrosine kinase activity (PubMed:1382974). Involved in DNA damage checkpoint control and for proper DNA damage repair (PubMed:18843199). In response to injury that includes DNA damage, NEK1 phosphorylates VDAC1 to limit mitochondrial cell death (By similarity). May be implicated in the control of meiosis (PubMed:1382974). Involved in cilium assembly (By similarity).[UniProtKB/Swiss-Prot Function]

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