Mouse Npr3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Npr3
Locus ID	18162
Kit Components	GA202953G1, Npr3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202953G2, Npr3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202953G3, Npr3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001039181, NM_001286395, NM_008728
Synonyms	ANP-C; ANPR-C; EF-2; lgj; NPR-C; stri
Summary	Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP (PubMed:10377427, PubMed:17951249). May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects (PubMed:10377427, PubMed:17951249). May regulate diuresis, blood pressure and skeletal development (PubMed:10377427). Does not have guanylate cyclase activity (PubMed:10377427).[UniProtKB/Swiss-Prot Function]

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