Mouse Prf1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Prf1
Locus ID	18646
Kit Components	GA203192G1, Prf1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203192G2, Prf1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203192G3, Prf1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_011073
Synonyms	Pfn; Pfp; Prf-1
Summary	Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes.[UniProtKB/Swiss-Prot Function]

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