Mouse Prkcsh activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Prkcsh
Locus ID	19089
Kit Components	GA203380G1, Prkcsh gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203380G2, Prkcsh gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203380G3, Prkcsh gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001293650, NM_001293651, NM_008925
Synonyms	80K-H; PKCSH
Summary	Regulatory subunit of glucosidase II that cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins (PubMed:27462106, PubMed:9148925). Required for efficient PKD1/Polycystin-1 biogenesis and trafficking to the plasma membrane of the primary cilia (PubMed:21685914).[UniProtKB/Swiss-Prot Function]

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