Mouse Ptcra activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ptcra
Locus ID	19208
Kit Components	GA203444G1, Ptcra gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203444G2, Ptcra gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203444G3, Ptcra gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_011195
Synonyms	gp33; pT-alpha; pT-alpha-TCR; pTa; pTalpha; pT[a]
Summary	The pre-T-cell receptor complex (composed of PTCRA, TCRB and the CD3 complex) regulates early T-cell development. Isoform 1 acts to retain most TCRB intracellularly, while isoform 2 permits higher levels of cell surface TCRB expression and facilitates signaling from the CD3-TCRB complex.[UniProtKB/Swiss-Prot Function]

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