Mouse Ptgs2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ptgs2
Locus ID	19225
Kit Components	GA203460G1, Ptgs2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203460G2, Ptgs2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203460G3, Ptgs2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_011198
Synonyms	Cox-2; COX2; gripghs; PES-2; PGHS-2; Pghs2; PHS-2; PHS II; TIS10
Summary	This gene encodes an enzyme that is a member of the prostaglandin G/H synthase family. The encoded protein converts arachidonic acid to prostaglandin endoperoxide H2 which is a key enzymatic step in prostaglandin biosynthesis. This gene is the inducible prostaglandin G/H synthase family member that is upregulated during inflammation. Aberrant regulation of this gene is associated with cancer progression in several tissues and an increased risk of cardiovascular events. This gene is the target of many non-steroidal anti-inflammatory drugs. [provided by RefSeq, Sep 2015]

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