Mouse Ptprk activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ptprk
Locus ID	19272
Kit Components	GA203493G1, Ptprk gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203493G2, Ptprk gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203493G3, Ptprk gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_008983, NM_001359355, NM_001359356
Synonyms	AI853699; PTPk; RPTPkappa
Summary	Regulation of processes involving cell contact and adhesion such as growth control, tumor invasion, and metastasis. Negative regulator of EGFR signaling pathway. Forms complexes with beta-catenin and gamma-catenin/plakoglobin. Beta-catenin may be a substrate for the catalytic activity of PTPRK/PTP-kappa.[UniProtKB/Swiss-Prot Function]

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