Mouse Nectin2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Nectin2
Locus ID	19294
Kit Components	GA203510G1, Nectin2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203510G2, Nectin2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203510G3, Nectin2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001159724, NM_008990
Synonyms	AI325026; AI987993; Cd112; MPH; nectin-2; Pvr; Pvrl2; Pvs
Summary	Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive. Probable cell adhesion protein.[UniProtKB/Swiss-Prot Function]

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.