Mouse Pex19 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Pex19
Locus ID	19298
Kit Components	GA203512G1, Pex19 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203512G2, Pex19 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203512G3, Pex19 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001159525, NM_023041, NM_001356513, NM_001356514
Synonyms	Pxf
Summary	Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53.[UniProtKB/Swiss-Prot Function]

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