Mouse Rad17 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rad17
Locus ID	19356
Kit Components	GA203546G1, Rad17 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203546G2, Rad17 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203546G3, Rad17 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001044371, NM_001283011, NM_011233
Synonyms	MmRad24
Summary	Essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. Has a weak ATPase activity required for binding to chromatin. Participates in the recruitment of the RAD1-RAD9-HUS1 complex and RHNO1 onto chromatin, and in CHEK1 activation. May also serve as a sensor of DNA replication progression, and may be involved in homologous recombination (By similarity). Essential for embryonic development. May be involved in homologous recombination.[UniProtKB/Swiss-Prot Function]

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