Mouse Reg3g activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Reg3g
Locus ID	19695
Kit Components	GA203606G1, Reg3g gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203606G2, Reg3g gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203606G3, Reg3g gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_011260
Synonyms	AI449515; REG-3-gamma; reg III-gamma
Summary	This gene encodes a C-type lectin that demonstrates bactericidal activity. This gene is predominantly expressed in the distal small intestine where the encoded protein undergoes proteolytic processing by trypsin. Mice lacking the encoded protein exhibit altered mucus distribution, increased bacterial contact with the epithelium, and elevated inflammatory markers in the ileum, and low-grade inflammation. [provided by RefSeq, Jun 2016]

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