Mouse Rfxank activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rfxank
Locus ID	19727
Kit Components	GA203628G1, Rfxank gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203628G2, Rfxank gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203628G3, Rfxank gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001025589, NM_011266
Synonyms	Tvl1
Summary	Activates transcription from class II MHC promoters. Activation requires the activity of the MHC class II transactivator/CIITA. May regulate other genes in the cell. RFX binds the X1 box of MHC-II promoters (By similarity). May also potentiate the activation of RAF1 (PubMed:10329666).[UniProtKB/Swiss-Prot Function]

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