Mouse Uri1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Uri1
Locus ID	19777
Kit Components	GA203646G1, Uri1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203646G2, Uri1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203646G3, Uri1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_011274
Synonyms	C80913; NNX3; Rmp
Summary	Involved in gene transcription regulation. Acts as a transcriptional repressor in concert with the corepressor UXT to regulate androgen receptor (AR) transcription. May act as a tumor suppressor to repress AR-mediated gene transcription and to inhibit anchorage-independent growth in prostate cancer cells. Required for cell survival in ovarian cancer cells. Together with UXT, associates with chromatin to the NKX3-1 promoter region (By similarity).[UniProtKB/Swiss-Prot Function]

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