Mouse Rtn2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rtn2
Locus ID	20167
Kit Components	GA203730G1, Rtn2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203730G2, Rtn2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203730G3, Rtn2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001025364, NM_013648
Synonyms	MMS10-P; Ms10p; Nspl1; NSPLI
Summary	Inhibits amyloid precursor protein processing, probably by blocking BACE1 activity (By similarity). Enhances trafficking of the glutamate transporter SLC1A1/EAAC1 from the endoplasmic reticulum to the cell surface (By similarity). Plays a role in the translocation of SLC2A4/GLUT4 from intracellular membranes to the cell membrane which facilitates the uptake of glucose into the cell (PubMed:19720795).[UniProtKB/Swiss-Prot Function]

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