Mouse Scn10a activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Scn10a
Locus ID	20264
Kit Components	GA203779G1, Scn10a gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203779G2, Scn10a gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203779G3, Scn10a gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001205321, NM_009134
Synonyms	Nav1.8; PN3; SNS
Summary	Tetrodotoxin-resistant channel that mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. Plays a role in neuropathic pain mechanisms.[UniProtKB/Swiss-Prot Function]

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