Mouse Sema3b activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Sema3b
Locus ID	20347
Kit Components	GA203832G1, Sema3b gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203832G2, Sema3b gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203832G3, Sema3b gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001042779, NM_001291537, NM_001291538, NM_001291539, NM_009153, NR_111986
Synonyms	SemA; sema5; Semaa; semaV
Summary	This gene encodes a secreted protein that belongs to the class 3 semaphorin/collapsin family. Members of this family play a role in growth cone guidance during neurogenesis. The encoded protein inhibits axonal extension. This protein is thought to be an osteoblast protein that regulates bone mass and affects skeletal homeostasis. A similar gene in humans functions as a tumor suppressor gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]

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