Mouse Spi1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Spi1
Locus ID	20375
Kit Components	GA203852G1, Spi1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203852G2, Spi1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203852G3, Spi1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_011355
Synonyms	Dis-1; Dis1; PU.1; Sfpi-1; Sfpi1; Spi-1; Tcfpu1; Tfpu.1
Summary	Binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing.[UniProtKB/Swiss-Prot Function]

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