Mouse Frzb activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Frzb
Locus ID	20378
Kit Components	GA203854G1, Frzb gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203854G2, Frzb gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203854G3, Frzb gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_011356
Synonyms	frezzled; fritz; Frp; frzb-1; Sfrp3
Summary	Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development (By similarity).[UniProtKB/Swiss-Prot Function]

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