Mouse St8sia3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	St8sia3
Locus ID	20451
Kit Components	GA203900G1, St8sia3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203900G2, St8sia3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203900G3, St8sia3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_009182
Synonyms	AI847333; Siat8c; ST8SiaIII
Summary	Catalyzes the transfer of sialic acid from a CMP-linked sialic acid donor onto the terminal sialic acid of an acceptor through alpha-2,8-linkages. Is active with alpha-2,3-linked, alpha-2,6-linked and alpha-2,8-linked sialic acid of N-linked oligosaccharides of glycoproteins and glycolipids. Displays preference for substrates with alpha-2,3-linked terminal sialic acid. It can form polysialic acid in vitro directly on alpha-2,3-, alpha-2,6-, or alpha-2,8-linked sialic acid.[UniProtKB/Swiss-Prot Function]

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