Mouse Slc4a1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Slc4a1
Locus ID	20533
Kit Components	GA203959G1, Slc4a1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203959G2, Slc4a1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203959G3, Slc4a1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_011403
Synonyms	Ae1; CD233; Empb3; l11Jus51
Summary	Functions both as a transporter that mediates electroneutral anion exchange across the cell membrane and as a structural protein. Major integral membrane glycoprotein of the erythrocyte membrane; required for normal flexibility and stability of the erythrocyte membrane and for normal erythrocyte shape via the interactions of its cytoplasmic domain with cytoskeletal proteins, glycolytic enzymes, and hemoglobin. Functions as a transporter that mediates the 1:1 exchange of inorganic anions across the erythrocyte membrane. Mediates chloride-bicarbonate exchange in the kidney, and is required for normal acidification of the urine.[UniProtKB/Swiss-Prot Function]

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