Mouse Spic activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Spic
Locus ID	20728
Kit Components	GA204070G1, Spic gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204070G2, Spic gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204070G3, Spic gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_011461
Synonyms	AU019198; C76795; Prf; Spi-C
Summary	Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. Regulates VCAM1 gene expression.[UniProtKB/Swiss-Prot Function]

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