Mouse Tbx6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tbx6
Locus ID	21389
Kit Components	GA204225G1, Tbx6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204225G2, Tbx6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204225G3, Tbx6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_011538
Synonyms	rv
Summary	T-box transcription factor that plays an essential role in the determination of the fate of axial stem cells: neural vs mesodermal. Acts in part by down-regulating, a specific enhancer (N1) of SOX2, to inhibit neural development. Seems to play also an essential role in left/right axis determination and acts through effects on Notch signaling around the node as well as through an effect on the morphology and motility of the nodal cilia.[UniProtKB/Swiss-Prot Function]

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