Mouse Mlx activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Mlx
Locus ID	21428
Kit Components	GA204252G1, Mlx gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204252G2, Mlx gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204252G3, Mlx gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001159384, NM_001159385, NM_011550
Synonyms	bHLHd13; Tcfl4; Tf4
Summary	Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MAD1, MAD4, MNT, WBSCR14 and MLXIP which recognizes the core sequence 5'-CACGTG-3'. The TCFL4-MAD1, TCFL4-MAD4, TCFL4-WBSCR14 complexes are transcriptional repressors. Plays a role in transcriptional activation of glycolytic target genes. Involved in glucose-responsive gene regulation.[UniProtKB/Swiss-Prot Function]

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