Mouse Terf1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Terf1
Locus ID	21749
Kit Components	GA204294G1, Terf1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204294G2, Terf1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204294G3, Terf1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001286628, NM_009352, NR_152944
Synonyms	Pin2; Trbf1; Trf1
Summary	This gene encodes a protein that binds to repeats in telomeres to form a nucleoprotein complex that protects against the degradation of chromosomal ends. The encoded protein regulates the length of telomeres and is an integral structural component of the functional telomere. This protein is thought to play a role in spindle formation in mitosis. Mutations in this gene are associated with bone marrow failure. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2013]

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