Mouse Tgfbr1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tgfbr1
Locus ID	21812
Kit Components	GA204323G1, Tgfbr1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204323G2, Tgfbr1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204323G3, Tgfbr1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_009370
Synonyms	Alk-5; ALK5; AU017191; ESK2; TbetaR-I; TbetaRI; TGFR-1
Summary	This gene encodes a member of the transforming growth factor beta (TGF-beta) receptor family of proteins. These proteins comprise one component of the TGF-beta signaling pathway, which transduces extracellular signals into gene expression changes to regulate a wide range of cellular responses, including proliferation, migration, differentiation and apoptosis. Homozygous knockout mice for this gene exhibit impaired angiogenesis and embryonic lethality. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]

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