Mouse Tnfsf12 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tnfsf12
Locus ID	21944
Kit Components	GA204399G1, Tnfsf12 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204399G2, Tnfsf12 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204399G3, Tnfsf12 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_011614
Synonyms	Apo3l; Dr3l; Dr3lg; Tweak
Summary	Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion (By similarity).[UniProtKB/Swiss-Prot Function]

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